Luis Enrique has announced his squad for the challenging trip to Madrid to take on Diego Simeone's Atlético on Sunday afternoon.
The manager is without Arda Turan, Mascherano and Aleix Vidal due to injury, while he has left out goalkeeper Masip for technical reasons.
The full list of 18 is therefore as follows: Ter Stegen, Cillessen, Piqué, Rakitic, Sergio, Denis Suárez, A. Iniesta, Suárez, Messi, Neymar Jr, Rafinha, Alcácer, Jordi Alba, Digne, Sergi Roberto, André Gomes, Umtiti and Mathieu.
Shortly before setting off, the team held their last training session ahead of Sunday's big game at Ciutat Esportiva.
Luis Enrique also spoke to the press, sharing his thoughts on what he feels will be "an important game for both sides".